禁食应激对心肌组织Fe、Mg、Zn、Cu含量的影响
作者：眭建 任春兰
单位：镇江医学院病理生理教研室 镇江 212001
关键词：禁食；应激；心肌
四川生理科学杂志000104摘 要：目的：观察禁食豚鼠不同时间心肌姐织Fe.Me.zn、Cu含量的变化，以揭示禁食应激对心肌组织金属元素代谢的影响及规律。方法：短毛种豚鼠24只，随机分为4组，正常组和实验组1、2、3，实验组分别禁食14、48、71小时。结果：(1)心肌组织内Fe、Mg水平随禁食时间的延长而下降。(2)心肌蛆组织中Cu平在禁食48小时48、71小时。结果：(1)心肌组织内Fe、Mg水平随禁食时间的延长而下降。(2)心肌 目的：观察禁食豚鼠不同时间心肌姐织Fe.Me.zn、Cu含量的变化，以揭示禁食应激对心肌组织金属元素代谢的影响及规律。方法：短毛种豚鼠24只，随机分为4组，正常组和实验组1、2、3，实验组分别禁食14、48、71小时。结果：(1)心肌组织内Fe、Mg水平随禁食时间的延长而下降。(2)心肌蛆组织中Cu平在禁食48小时后上升.(3)而Z水平在禁食早期明显上升，以后下降至正常。P均Myocardial Fe. Mg,Zn and Cu Contents in Starvating Guinea Pigs.
, http://www.100md.com
Sui Jian ,Ren Chunlan
(Department of Pathophysiology, Zhenjiang Medical College, Zhenjiang 212001)
Abstract：To study the relatlonship between starvating and the myccardial Fe,Mg, Zn, Cu oontents.The effect of starvafing on myocardial Fe. Mg. Zn, Cu eontents in guinea pigs was observed. Method: Twenty-roar guinea pigs were derided randomly into no-starvating group as comparvating, starvating 24hr group.48hr group and 72hrgroup respectively as expermotal group. Results: 1, Myocardial Fe. Mg, Zn and Cu contents lowered along with thecontinunitv of hunger. 2. Cu content increased in experimental groups. 3. Zn oontent increased at the early stage of starvating but decreased to nomal level afterwards, Conclusion;1. Starvaing do effect distribution andmetabolism of myocardial Fe,Mg. Zn. Cu, 2. Myocardial Fe. Mg. Zn.Cu contents and stress response may have interelation.
, 百拇医药
Keywords：starvation;stress;myocardium
参考文献：
[1]眭建，汪玉芳.饥饿豚鼠应激性心律失常的观察.中国心理卫生杂志，1995；9(1)：13
[2]郑永章，秦荣大等编译.卫生检验方法手册.北京：北京大学出版社，1990
[3]金有余，等.临床生化检验学.北京：海洋出版社，1993
[4]林其燧，文庆成.临床化学诊断方法大全.北京：北京大学出版社，1990
[5]Balhntyne GH; Fitzsimons EJ. Acute hypoferremia fallowlng cardiac surgey. Am Surg, 1984 ;50 ( 8 ): 450
, http://www.100md.com
[6]Fisler JS. Cardiac effects of starvation and semistravation,diets:safety and mechanisms of action.
[7]Fiink EB. Magnesium defieieney: etiolcy and cincal. Acta Med Scand Suppl, 1981;647:125
[8]Tuffe LS, Nockels CF, Fetlrnan MJ. Effects oF Escherichia Coli on iron, Copper, and metabolism in chicks. AVianDis, 1988; 32(4): 779
[9]Powell SR, Hall D, Aiuto L et al. Zine improves postischemic recovery of isolated rat hearts inhibition,of oxidative stress. Am J Physiol, 1994;6(2) :2497
, 百拇医药
[10]Elln RJ. Magnesium metabolism in health and disease. Dis Mon, 1988;34(4):161Elln RJ. Magnesium metabolism in health and disease. Dis Mon, 1988;34(4):161
[11]Brenmer I. Interations between metallothionem and trece elements. Prog?Food Nun Brenmer I. Interations between metallothionem and trece elements. Prog?Food Nun Sci, 1987; 11(1): 1
[12]CaIivello G, RiOci P, Lauro L et al. Mg deficiency induces mineral content changes and oxidative stress in rais.Biochem.Mol Biol Iht, 1994; 32(5) :903
[13]Henrotte JG. Genetic regUlation of blool and tissue magnesium content in marmmals.Magnesium, 1988;7(5`6):306
[14]Naeve GS, Vana AM, Eggold JR, et al. Expression profile of the copper homeotstasis gene, rAIoxl, in the ratbrain. Neuroscience, 1999;93(3):1179, http://www.100md.com
单位：镇江医学院病理生理教研室 镇江 212001
关键词：禁食；应激；心肌
四川生理科学杂志000104摘 要：目的：观察禁食豚鼠不同时间心肌姐织Fe.Me.zn、Cu含量的变化，以揭示禁食应激对心肌组织金属元素代谢的影响及规律。方法：短毛种豚鼠24只，随机分为4组，正常组和实验组1、2、3，实验组分别禁食14、48、71小时。结果：(1)心肌组织内Fe、Mg水平随禁食时间的延长而下降。(2)心肌蛆组织中Cu平在禁食48小时48、71小时。结果：(1)心肌组织内Fe、Mg水平随禁食时间的延长而下降。(2)心肌 目的：观察禁食豚鼠不同时间心肌姐织Fe.Me.zn、Cu含量的变化，以揭示禁食应激对心肌组织金属元素代谢的影响及规律。方法：短毛种豚鼠24只，随机分为4组，正常组和实验组1、2、3，实验组分别禁食14、48、71小时。结果：(1)心肌组织内Fe、Mg水平随禁食时间的延长而下降。(2)心肌蛆组织中Cu平在禁食48小时后上升.(3)而Z水平在禁食早期明显上升，以后下降至正常。P均Myocardial Fe. Mg,Zn and Cu Contents in Starvating Guinea Pigs.
, http://www.100md.com
Sui Jian ,Ren Chunlan
(Department of Pathophysiology, Zhenjiang Medical College, Zhenjiang 212001)
Abstract：To study the relatlonship between starvating and the myccardial Fe,Mg, Zn, Cu oontents.The effect of starvafing on myocardial Fe. Mg. Zn, Cu eontents in guinea pigs was observed. Method: Twenty-roar guinea pigs were derided randomly into no-starvating group as comparvating, starvating 24hr group.48hr group and 72hrgroup respectively as expermotal group. Results: 1, Myocardial Fe. Mg, Zn and Cu contents lowered along with thecontinunitv of hunger. 2. Cu content increased in experimental groups. 3. Zn oontent increased at the early stage of starvating but decreased to nomal level afterwards, Conclusion;1. Starvaing do effect distribution andmetabolism of myocardial Fe,Mg. Zn. Cu, 2. Myocardial Fe. Mg. Zn.Cu contents and stress response may have interelation.
, 百拇医药
Keywords：starvation;stress;myocardium
参考文献：
[1]眭建，汪玉芳.饥饿豚鼠应激性心律失常的观察.中国心理卫生杂志，1995；9(1)：13
[2]郑永章，秦荣大等编译.卫生检验方法手册.北京：北京大学出版社，1990
[3]金有余，等.临床生化检验学.北京：海洋出版社，1993
[4]林其燧，文庆成.临床化学诊断方法大全.北京：北京大学出版社，1990
[5]Balhntyne GH; Fitzsimons EJ. Acute hypoferremia fallowlng cardiac surgey. Am Surg, 1984 ;50 ( 8 ): 450
, http://www.100md.com
[6]Fisler JS. Cardiac effects of starvation and semistravation,diets:safety and mechanisms of action.
[7]Fiink EB. Magnesium defieieney: etiolcy and cincal. Acta Med Scand Suppl, 1981;647:125
[8]Tuffe LS, Nockels CF, Fetlrnan MJ. Effects oF Escherichia Coli on iron, Copper, and metabolism in chicks. AVianDis, 1988; 32(4): 779
[9]Powell SR, Hall D, Aiuto L et al. Zine improves postischemic recovery of isolated rat hearts inhibition,of oxidative stress. Am J Physiol, 1994;6(2) :2497
, 百拇医药
[10]Elln RJ. Magnesium metabolism in health and disease. Dis Mon, 1988;34(4):161Elln RJ. Magnesium metabolism in health and disease. Dis Mon, 1988;34(4):161
[11]Brenmer I. Interations between metallothionem and trece elements. Prog?Food Nun Brenmer I. Interations between metallothionem and trece elements. Prog?Food Nun Sci, 1987; 11(1): 1
[12]CaIivello G, RiOci P, Lauro L et al. Mg deficiency induces mineral content changes and oxidative stress in rais.Biochem.Mol Biol Iht, 1994; 32(5) :903
[13]Henrotte JG. Genetic regUlation of blool and tissue magnesium content in marmmals.Magnesium, 1988;7(5`6):306
[14]Naeve GS, Vana AM, Eggold JR, et al. Expression profile of the copper homeotstasis gene, rAIoxl, in the ratbrain. Neuroscience, 1999;93(3):1179, http://www.100md.com